Ivica Klapan

Prof. dr.sc. Ivica Klapan dr. med.

Professor Ivica Klapan, M.D., Ph.D.

Degree, Vocation and Occupation:
Professor, MD, PhD, Scientific adviser; Professor of Otorhinolaryngology, Head and Neck Plastic Surgery, School of Medicine, University of Zagreb, and School of Medicine, Josip Juiraj Strossmayer University in Osijek, Republic of Croatia, EU
Medical Licensure : MD No. 040622 (approved by the Croatian Medical Council)

Surgical and Scientific Fields of Interest: rhinosinusology, functional endoscopic sinus surgery (FESS), plastic and reconstructive surgery of the head and neck, 3D navigation-computer assisted FES-surgery (3D-CA-NESS), telesurgery (tele-3D-CA-NESS), virtual endoscopy and surgery (VE, VS) of the head and neck, chronic sinusitis – immunobiochemical characteristics, rhinophotodynamic therapy (RPDT) of sinonasal polyposis

Fields of Expert Activities: rhino surgery (nose/sinuses/skull base), plastic and reconstructive surgery of the head and neck, functional endoscopic sinus surgery (FESS),3D-navigation-computer assisted FES-surgery (3D-CA-NESS), computerized plastic reconstructive surgery (C-FPS)

Residency, Sub-residency, Education:
1978-1983 Medical School, University of Zagreb, Croatia, EU
1983 Thesis "Conversion of solid neoplasms into ascites tumors", Department of Physiology and Immunology, School of Medicine, University of Zagreb, Croatia (mentor: Prof. Dr. Filip Čulo)
1983-1986 Postgraduate Study "Clinical Immunology and Allergology", School of Medicine, University of Zagreb, Croatia, EU
1986 Master's Degree (MMS) "The influence of cyclophosphamide on tumor-specific immunity. Induction of antitumor immunity in mice bearing advanced tumor", Department of Physiology and Immunology, School of Medicine, University of Zagreb, Croatia, EU (mentor: Prof. Dr. Filip Čulo)
1986-1989 Residency Department of Otorhinolaryngology, Head and Neck Surgery, School of Medicine, University of Zagreb/Zagreb University Clinical Hospital Center, Šalata 4, Zagreb, Croatia, EU, and 
1989-1990 Eye and Ear Institute, Department of Otorhinolaryngology–Head & Neck Surgery, University of Pittsburgh, Pittsburgh, PA, USA
1987-1989 Postgraduate Study "Otorhinolaryngology, Head and Neck Surgery", School of Medicine, University of Zagreb
1990 (May) Doctor's Degree (PhD), "Prognostic significance of in vivo and in vitro prostaglandin E2 production by squamous cell carcinoma of the head and neck", Department of Otorhinolagyngology-Head and Neck Surgery, School of Medicine, University of Zagreb, Croatia (mentor: Prof. Dr. Vladimir Katic), Eye and Ear Institute, Department of Otorhinolaryngology–Head & Neck Surgery, University of Pittsburgh, Pittsburgh, PA, USA (mentors: Prof. Dr. Jonas T. Johnson and Prof. Dr. Carl H. Snyderman), and Division of Head and Neck Oncology and Immunology, and Immunologic Monitoring and Diagnostic Laboratory, Pittsburgh Cancer Institute, University of Pittsburgh, PA, USA (mentor: Prof. Dr. Theresa L Whiteside). 
1990 (Dec.) Specialization, Otorhinolaryngology- Head and Neck Surgery , Department of ENT, Head and Neck Surgery, University Clinical Hospital Center "Sisters of Charity", Zagreb, Croatia, EU
1990-1992 Sub-residency , Head and Neck Plastic Surgery, Department of ENT, Head and Neck Surgery, School of Medicine, University of Zagreb, and Zagreb University Clinical Hospital Center, Šalata 4, Zagreb, Croatia, EU

Education/Training at a Number of Renowned International Departments and Institutes:
1989-1990 Eye & Ear Institute, Department of Otorhinolaryngology–Head & Neck Surgery, University of Pittsburgh, Pittsburgh, PA, USA
1989-1990 Division of Head and Neck Oncology and Immunology, and Immunologic Monitoring and Diagnostic Laboratory, Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, USA
1993 University ENT-Clinic, LKH Graz, Austria, EU
1994 The Institute of Laryngology and Otology With the Ferens, London, Great Britain, EU
1997 Cottle International Rhinology Centennial, Phyladelphia, PA, USA

Professional Positions, Employment After Residency: 
1990 Assistant, cumulative employment, clinical-scientific field of ENT, Head and Neck Surgery, Zagreb University School of Medicine, and Department of Otorhinolaryngology, H&N Surgery, University Clinical Hospital Center Zagreb
1996 Assistant Professor, cumulative employment, clinical-scientific field of ENT, head and neck surgery; Zagreb University School of Medicine, and Department of Otorhinolaryngology, H&N Surgery, University Clinical Hospital Center Zagreb
2000 Associate Professor, cumulative employment, clinical-scientific field of ENT, head and neck surgery; Zagreb University School of Medicine, and Department of Otorhinolaryngology, H&N Surgery, University Clinical Hospital Center Zagreb
2000 Visiting Professor, Eye and Ear Institute, Department of Otorhinolaryngology, Head and Neck Surgery, University of Pittsburgh, Pittsburgh, PA, USA 
2000 Distinguished Faculty, Mayo Clinic, and American Rhinologic Society, Washington, D.C., USA 
2004 Professor, cumulative employment, clinical-scientific field of ENT, head and neck Surgery; Zagreb University School of Medicine, and Department of Otorhinolaryngology, H&N Surgery, University Clinical Hospital Center Zagreb
2004 Visiting Professor , Department of Cranio-Maxillo-Facial Surgery, Bavarian Julius Maximillian University, Würzburg, Germany
2009 Professor, cumulative employment, clinical-scientific field of ENT, head and neck Surgery; Josip Juraj Strossmayer University School of Medicine in Osijek

Duties, Selected Administrative, Advisory, and Honorary Posts:
1998-2009 Head, Reference Center of Computerized Surgery & Telesurgery, Ministry of Health and Social Welfare, Republic of Croatia, EU
2000-2017 Head, Course on Telemedicine, Scientific Postgraduate Study at School of Medicine, University of Zagreb, Zagreb
2000-2009 Chairman, Croatian Society of Telemedicine, Croatian Medical Association (CMA)
2004-2007 Chairman, Commission on Telemedicine, Ministry of Health and Social Welfare, Republic of Croatia
2006-2009 President, Section of Rhinology, Croatian Medical Association (CMA)
2007 Chair, Department of Otorhinolaryngology, Head and Neck Surgery, Šalata 4, School of Medicine, University of Zagreb
2007-2017 Head, Course on Telemedicine, scientific postgraduate study at School of Medicine, J. J. Strossmayer University, Osijek
2015-2017 Secretary, Croatian Rhinology Society (CRS)
2017 Editorial Board Member, IL Journal of Otolaryngology and Rhinology, Wilmington, DE, USA
2017 Editorial Board Member, Frontiers in Otolaryngology-Head and Neck Surgery (FOHNS) Applis Publishers, Scottsdale, AZ, USA. 

Long-Standing Member:
American Academy of Otorhinolaryngology-Head&Neck Surgery (AAO-HNS)
American Society for Laser Medicine and Surgery (ASLMS)
American Telemedicine Association (ATA)
New York Academy of Sciences, NY, USA
European Rhinologic Society (ERS) - International Advisory Board
International Society for Computer Aided Surgery, USA (ISCAS)
European School of Oncology (ESO)
European Association for Cancer Research (EACR)
European Academy of Facial Plastic Surgery (EAFPS)
Croatian Society of Plastic, Reconstructive and Cosmetic Surgery (CMA)

Admitted as Full Member to the Most Prestigious International Medical Academies/ Commissions/Societies:
Collegium Otorhinolaryngologicum Amicitiae Sacrum (CORLAS)
Royal Society of Medicine of Great Britain (London)
Board, International Society for Telemedicine and e-Health (ISfTeH; Luxembourg)
International Confederation for Plastic Reconstructive and Aesthetic Surgery
European Academy of ORL and Head & Neck Surgery (EAORL-HNS)

Membership in the Most Prestigious Croatian National University Boards:
2004-2007 National Board for University Education of the Republic of Croatia
2009-2010 Accreditation Board of the Agency for Science and University Education of the Republic of Croatia

Scientific Projects:
4 (four) Croatian Projects; Team member,
10 (ten) Croatian Projects; Principal Investigator, launched by the Ministry of Science, Croatia, and
2 (two) USA Projects; Team member

Invited Lectures:
>350 lectures (invited lecturer, moderator, president), held at numerous universities, academies, international congresses, symposia and surgical courses in the USA, EU, Asia and Australia, organized by International Federation of ORL Societies (IFOS), European Federation of ORL Societies (EUFOS), European Rhinologic Society (ERS), American Rhinologic Society (ARS), and European Academy of ORL and Head & Neck Surgery (EAORL-HNS).

Professional Success in Medical Practice:
1992
Klapan I et al. Prognostic significance of plasma PGE concentration in patients with head and neck cancer. J Cancer Res Clin Oncol 1992;118:308-13 , chosen by the Editorial Department of Clinical Digest Series – Oncology Digest, Northbrook, IL, USA, have been published in an abridged form as being highly relevant for the scientific field of ENT
1994 The first 3D-navigation-computer assisted functional endoscopic nose and sinus operation (3D-CA-NES) in Croatian medicine, as one of the first operations of this type in the world (June 3rd)
1994 Klapan I et al. Acute upper respiratory tract infections and indications for tonsillectomy in children. I. Immunoglobulin synthesis in the palatine tonsil tissue. Int J Pediatr Otolaryngol 1994;29:169-78, chosen by the Editorial Department of Clinical Digest Series – Oncology Digest, Northbrook, IL, USA, have been published in an abridged form as being highly relevant for the scientific field of ENT
1995 The set hypothesis on the possible effect of AAm leukotriene C4 (LTC4) on creating conditions for the development of paranasal sinus mucosa lesions, and thus for the onset of sinonasal polyps (SNp), was subsequently fully confirmed; published in the leading medical periodicals (Am J Otolaryngol, 1995; CC)
1996 The first formal telemedicine (tele-radiology-otorhinolaryngology) video conference in Croatia (May)
1998 The first Tele-3D-navigation-computerized-endoscopic operations of the nose, sinuses and scull base (Tele-3D-CA-NES), for the first time in the world medicine, thus initiating a completely new era in the development of 21st century medicine worldwide. This achievement has been acknowledged by a special note in the American Academy of Otolaryngology – Head & Neck Surgery Monograph,
1999 Klapan I et al. Azithromycin and amoxicillin/clavulanic acid in the treatment of acute sinusitis. Am J Otolaryngol 1999;20:7-11 has been chosen by Pfizer, Inc., USA and Grupo Editorial Moreira and Journal Revista Brasileira de Medicina, Brazil, for special issuing and use in the USA and Brazil for its high relevance for the scientific field of ENT

Other Scientific and Clinical Activities:
1983 Effect of cytostatics on antitumor immunity in mice carrying advanced tumors (tumor-specific immunity)
1984 Induction of antitumor immunity after local (non-systemic) transfer of spleen cells in mice carrying advanced tumors
1986-1998 Determination of synthesis and prognostic significance of prostaglandin E (PGE) in vitro in patients with squamous cell carcinoma of the head and neck
1989-1990 In vivo and in vitro determination of PGE2 synthesis in monocellular lines of the head and neck squamous cell carcinoma
1989-1990 Antiproliferative (antitumor) effects of cytokines (IFN-γ, IFN-α, TNF-α) on the growth of head and neck squamous cell carcinoma
1990-1991 Rhinomanometry and septoplasty in children, immune basis of secretory otitis, adenoidectomy and pharyngotympanic tube dysfunction
1991 Comparison of US and radiologic studies with sinusoscopy findings in patients with maxillary sinusitis, indications for tonsillectomy, and immunoglobulin synthesis in palatine tonsils
1992 Determination of blood LBSA and histamine in patients with head and neck squamous cell carcinoma
1993 Biochemical analysis of arachidonic acid metabolite (AAm) synthesis in the tissue of vocal cord polyps and hypertrophic ventricular folds
1993-1994 Determination and role of arachidonic acid metabolites (AAm) in the tissue of sinonasal polyps and their prognostic value, endoscopic approach to metal foreign bodies in the nose and paranasal sinuses (3D-computerized surgery), comparison of rhinomanometry findings in patients with perennial rhinitis treated by CO2 laser turbinotomy and fluticasone propionate, paranasal sinuses and fibrous dysplasia
1996-1998 Therapeutic efficacy of 3-day azithromycin and 10-day amoxicillin/clavulanic acid therapy for acute sinusitis
1993-2000 Development of the original idea and method for the use of computerized support in cosmetic plastic surgery
1994 Development of a completely new type of surgery, "3D-computer assisted functional endoscopic sinus surgery (3D CA-NES)", preoperative planning, intraoperative guidance and postoperative analysis
1992-2016 The use of 3D-digitalizer in 3D CA-NES-operations
2003-2004 Effect of nonspecific prognostic tumor markers (Ki-67) on the growth, treatment and cure of the head and neck squamous cell carcinoma
1996-2017 Tele-3D-CA-NES
2000-2017 Development of telemedicine in the head and neck diagnosis and surgery
2005-2017 The use of sophisticated techniques of virtual reality (VR) in the head and neck diagnosis and surgery
2007-2017 Head and neck virtual diagnosis and surgery
2010-2017 Application of the newest techniques of virtual reality (VR) in the surgery of the nose, paranasal sinuses and scull base: (computer assisted navigation, marker-based virtual reality simulation, 3D-surgical planner with remote visualization, 3D-navigation and augmented reality in the operating room)

Original Publications:
(total: >110; citations: >400; h-index: >25; 14 medical books (7/Croatian and 7/English language; editor, author and/or co-autor)

Selected Nineteen (19) Original Publications: 
1 Klapan I, Čulo F, Marić M. The influence of cyclophosphamide on tumor-specific immunity. Induction of antitumor immunity in mice bearing advanced tumor. Period Biologorum, 1986, 88:526-527.
2 Sacchi M, Klapan I, Johnson JT, Whiteside TL. Antiproliferative effects of cytokines on squamous cell carcinoma . Arch Otolaryngol Head Neck Surg, 1991, 117:321-326.
3 Čulo, F; Klapan, I; Katić, V; Kolak, T; Bakula, B. Production of prostaglandin E by squamous carcinoma of the head and neck and adenocarcinoma of gastrointestinal tissue. // Medical oncology and tumor pharmacotherapy. 9 (1992) , 1; 35-39
4 Klapan I, Katić V, Čulo F, Ćuk V. Prognostic significance of plasma prostaglandin E concentration in patients with head and neck cancer. // Cancer Res Clin Oncol, 1992, 118:308-313.
5 Klapan I, Katić V, Čulo F, Sabolović D, Ćuk V, Fumić K, Simović S. Lipid bound sialic acid, PGE and histamine in head and neck cancer. // Eur J Cancer, 1993, 29A(6):839-845.
6 Čulo F, Klapan I, Kolak T. The influence of cyclophosphamide on anti-tumor immunity in mice mearing late stage tumors. I. Induction of anti-tumor immunity demonstrable upon local but not systemic transfer of spleen cells. Cancer Immunol Immunother, 1993, 36:115-122.
7 Snyderman CH, Klapan I, Milanovich M, Heo DS, Wagner R, Schwartz D, Johnson JT, Whiteside TL. Comparison of in vivo and in vitro prostaglandin E2 production by squamous cell carcinoma of the head and neck. Otolaryngol Head Neck Surg, 1994, 111:189-196.
8 Klapan I, Čulo F, Čulig J, Bukovec Ž, Simović S, Ćuk V, Rišavi R, Bumber Ž, Šprem N, Vukoja M. Arachidonic acid metabolites and sinonasal polyposis. I. Possible prognostic value. Am J Otolaryngol, 1995, 16(6):396-402.
9 Klapan I, Matrapazovski M, Orešković K, Čulig J. Azithromycin and amoxicillin/calvulanic acid in the treatment of acute sinusitis. Am J Otolaryngol, 1999, 20:7-11.
10 Klapan I, Šimičić Lj, Rišavi R, Bešenski N, Bumber Ž, Stiglmajer N, Janjanin S. Dynamic 3D computer-assisted reconstruction of metallic retrobulbar foreign body for diagnostic and surgical purposes. Case report: orbital injury with ethmoid bone involvement. . // Orbit, 2001, 20(1):35-49.
11 Klapan I, Šimičić Lj, Bešenski N, Bumber Ž, Janjanin S, Rišavi R, Mladina R. Application of 3D Computer -Assisted Techniques to Sinonasal Pathology-Case Report: War Wounds of Paranasal Sinuses Caused by Metallic Foreign Bodies . Am J Otolaryngol, 2002, 23(1):27-34.
12 Klapan I, Šimičić Lj, Rišavi R, Pasari K, Sruk V, Schwarz D, Barišić J. Real time transfer of live video images in parallel with three-dimensional modeling of the surgical field in computer-assisted telesurgery. . // Telemed Telecare, 2002, 8:125-130.
13 Klapan I, Šimičić Lj, Rišavi R, Bešenski N, Pasarić K, Gortan D, Janjanin S, Pavić D, Vranješ Ž. Tele-3D-Computer Assisted Functional Endoscopic Sinus Surgery: new dimension in the surgery of the nose and paranasal sinuses.. // Otolaryngology Head Neck Surg, 2002, 127:549-557.
14 Klapan I, Vranješ Ž, Rišavi R, Šimičić Lj, Prgomet D, Glušac B. Computer assisted surgery and computer-assisted telesurgery in otorhinolaryngology. Ear Nose Throat J, 2006, 85(5):318-321.
15 Klapan I, Vranješ Ž, Prgomet D, Lukinović J. Application of advanced virtual reality and 3D computer assisted technologies in tele-3D-computer assisted surgery in rhinology. // Coll Antropol, 2008, 32(1):217-219.
16 Raos P, Klapan I, Galeta T. Additive Manufacturing of Medical Models – Applications in Rhinology. Collegium Antropol, 2015; 39(3):667-73.
17 Klapan I, Raos P, Galeta T, Kubat G. Virtual reality in rhinology-a new experience of clinical experience.  Ear Nose Throat, 2016; 95(7): 23-28.
18 Klapan I, Duspara A, Majhen Z, Benić I, Kostelac M. What is the future of minimally invasive sinus surgery: computer assisted navigation, 3D-surgical planner or augmented reality in the operating room with contactless 'in the air' surgeon's commands? IL Journal of Otolaryngology and Rhinology, 2017;1(1):1-7.
19 Klapan I, Duspara A, Majhen Z, Benić I, Kostelac M, Kubat G, Berlengi N. What is the future of minimally invasive surgery in rhinology: marker-based virtual reality simulation with touch free surgeon's commands, 3D-surgical navigation with additional remote visualization in the operating room, or ...? Frontiers in Otolaryngology-Head and Neck Surgery (FOHNS). 2017. (submitted for publication)


Editorial Work in Scientific Journals:

Editorial Board Member, IL Journal of Otolaryngology and Rhinology, Wilmington, DE, USA
Editorial Board Member, Frontiers in Otolaryngology-Head and Neck Surgery (FOHNS)
Reviewer of numerous research projects launched by the Ministry of Science and Technology, Republic of Croatia, and papers submitted for publication to Croatian and American scientific CC medical journals. Supervisor to many graduation and MS theses and doctoral dissertations

Selected Five (5) Awards (of all fourteen; 14) international medical awards, recognitions and grants from the USA, Europe and Australia)
1989 Pittsburgh, PA, USA; only one award per year is granted by this American University 
1996 The Garnett Passe & Rodney Williams Memorial FoundationAward, Sydney, Australia, as one of the most prestigious World Congress of Otorhinolaryngology and Head and Neck Surgery awards, presented at the ceremony held in the Opera House, Sydney, led by Her Majesty Elisabeth II's Governor-General of Australia; the award was presented by Professor E. Myers, MD, PhD, Chairman of the American Academy of Otolaryngology – Head and Neck Surgery, USA
2009 Acknowledgment of high contribution to fostering the noble tradition of the Croatian Medical Association, medical science and healthcare in the Republic of Croatia, granted by a decision of the Main Board of the Croatian Medical Association (CMA)
2014 European Rhinologic Society-Society
Information (www.europeanrhinologicsociety.org/society_information.php) - " Professor Ivica Klapan, Croatia, EU, gave a significant contribution to the development of image-guided sinus surgery and computer-assisted surgery "
2014/2017 RECOGNITION OF EXCELLENCE - PATIENTS CHOICE : "Based on the preset criteria, analysis of evaluation and comments on all doctors (physicians) in the Republic of Croatia, available at the www.najdoktor.com portal, Professor Ivica Klapan, M.D., Ph.D., has been chosen as one of the best doctors according to patients' choice, and also as the superior ENT specialist/head and neck plastic surgeon in 2014, 2015 and 2016. The list of all doctors chosen by patients is available at http://najdoktor.com/najbolji-lijecnici-po-preporukama-pacijenata/a223#&panel1-2 "

Language Proficiency:
Croatian, mother tongue
English, and Italian (fluently)

Diplomas of honor and recognitions

Participation

Head/invited speaker of international congresses, surgical symposia, courses

2016. Zagreb, Croatia, EU, 4th Croatian Rhinology Congress, I. Klapan (faculty/congress secretary/workshop moderator/Workshop "NESS")

2014. Dubai, UAE, ISIAN-IRS-PARS, I. Klapan (faculty/invited resource speaker lecturer/Symposium „Recent and Advances in ESS“) 

2014. Istanbul, Turkey, Collegium ORLAS, I. Klapan (faculty/invited resource speaker lecturer/Symposium „Rhinology“)

 2014. Zagreb, Croatia, EU  3rd Croatian Rhinologic Congress, I. Klapan (faculty/congress secretary/workshop chairman)

2013. Nica, France, 2nd EAORL-HNS, 2nd CE-ORL, I. Klapan (faculty/invited resource speaker /symposium lecturer/CAS instructional course chairman) 

2012. Toulouse, France, 24th ERS & ISIAN, I. Klapan (faculty/invited resource speaker lecturer/CAS instructional course chairman)

2012, Zagreb, Croatia, 2nd Rhino Congress, I. Klapan (faculty/ invited resorce speaker/lecturer, CAS symposium president) and Prof. M. Caversaccio, Switzerland

2010, Zagreb, Croatia, 1st Rhino Congress, Prof. I. Klapan (faculty/invited resorce speaker/lecturer, CAS symposium president) 

2010, Leipzig, Germany, IRDC R&D Carl STORZ Center for Surgical Technology (invited/guest)

2010. Geneva, Swiss., 23rd ERS & ISIAN, I. Klapan (faculty/invited resource speaker) and Prof. G. Strauss, Germany

2009, Lepizig, Germany, Acqua Clinic, (invited/guest)

2008. Budapest, Hungary, 1st Rhinolight Masterclass (faculty, invited resource speaker/lecturer)

2007. Paris, France, Congress, Anti-aging treatment

2006. Island of Hvar, Croatia, 2nd International CRO TeleMED Congress (congress president)

2006. Vienna, Austrija, Austrian WG TeleMED e-Health, (invited speaker)

2006. Tampere, Finland, 21st ERS & ISIAN, (faculty/invited resource speaker/lecturer)

2005. Luxembourgh, 10th Med-e-Tel & ISfTeHealth, (faculty, invited resource speaker/lecturer)

2005. Tromso, Norway, High-Level European eHealth Conferrence, (representative/Republic of Croatia)

2005. Athens, Greece, EUFOS (ORL) Congress, I. Klapan (faculty/invited resource speaker/lecturer) i Prof. Naser Kotby (IFOS president)

2005. Roma, Italy, 18th IFOS (ORL) World Congress (faculty, invited resource speaker/lecturer)

2004. Zagreb, Croatia, 2nd International Croatian Telemed Congress (congress president)

2004. Rodos, Greece,  5th EUFOS Congress (faculty, invited resource speaker/lecturer,  representative / Republic of Croatia)

 2003.  Warsaw, Poland, Rhinology Masterclass (faculty/invited resource speaker/lecturer)

2003. Seoul, South Korea, IRS & ISIAN (ORL) (faculty, invited resource speaker/lecturer, CAS symposium president)

2002. Bangkok,Thailand, National Medical Center

2002.  Makarska, Croatia, 1st International Croatian Telemed Congress (congress president)

2001. Athens, Greece, 2nd World Congresss of ORL, Allergy, Endoscopic Surgery (faculty, invited  resource speaker/lecturer)

2001. Ancona, Italy, International  TeleMED Conferrence (conferrence president)

2001. Aalborg, Denmark, ORL Department (invited speaker, guest)

2001. Bari, Italy, SoftCOM Conferrence (conferrence president)

 2000. Washington DC, USA,  World Congress of the Nose (faculty/ invited resource speaker/lecturer, workshop president)

 2000. Berlin, Germany, 4th EUFOS (faculty, invited speaker)

2000. Barcelona, Spain, 18th ERS & ISIAN (ORL) (faculty/invited resource speaker/lecturer, CAS symposium presidentt) 

2000. Pittsbourgh, PA, USA, International Symposium "Cancer of the Oral Cavity" (faculty/invited resource speaker/lecturer)

 2000. Pittsbourgh, PA, USA, Professor E. Myers (chairman/ Eye&Ear Dept., University of Pittsbourgh),  "Visiting Professor" diploma/professor Klapan

1999/2000. Island of Brač, Croatia, TeleMED Conferrence Brač-EU (conferrence president), with dr. Slender (director, MC Brač) 

1999. Manila, Phillipines, 18th ISIAN (ORL), I. Klapan (faculty/invited resource speaker/lecturer, CAS symposium president) & Prof. G. Vincente (congress president)

1998. San Antonio, TX, USA, 102nd Annual Meeting American Academy ORL-H&N Surgery

1998. Viena, Austria, 17th ERS & ISIAN (ORL) (faculty/invited speaker) 

1997. Sydney, Australia, World Congress of ORL Head & Neck Surgery (World Congress / faculty / invited resource speaker/lecturer) 

1997. Portorož, SLO, 4th Int. Endoscop. Congress (invited speaker)

1996. Moscow, Russia, 3rd Russian Congress „The Men & Pharmacy“ (faculty, invited resource speaker/lecturer)